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(83) reported significant improvements in motor function, as well as potential reductions in non-motor symptoms in PD patients treated with exenatide (83)

Mater 34 (45), 2206286

GLP-1 activates the GLP-1R to stimulate adenylate cyclase (AC), increasing intracellular levels of cyclic AMP (cAMP) (Sandoval and DAlessio, 2015)

Those trials suggest that, while perhaps not quite as impressive as its injectable peptide cousins, the drug is still safe and effective at inducing significant weight loss