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Intermittent claudication in peripheral arterial disease In peripheral arterial disease, atherosclerosis of the arteries that supply the lower extremities may diminish blood flow to the point that the metabolic needs of exercising muscles are not sufficiently met, thereby leading to ischemic leg or hip pain known as claudication (see the page on Intermittent Claudication in Peripheral Arterial Disease) (63)

[PMID: 16507568] PubMed record related to this compound for laboratory literature review

Fe 2+ in the cytoplasm and mitochondria establishes a labile iron pool (LIP), and through the mediation of Fenton reaction-induced LPO, it shows oxidative activity and induces ferroptosis

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