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The medication works through a dual mechanism of action as both a glucose-dependent insulinotropic polypeptide (GIP) receptor agonist and a glucagon-like peptide-1 (GLP-1) receptor agonist
Both represent meaningful improvements, but the 15-pound difference translates to additional health benefits
doi: 10.14348/molcells.2023.2192 50
On tolerability, retatrutide's GI adverse event rate is higher than tirzepatide's at matched mechanistic dose, which is the tradeoff for the additional mechanism
compounded tirzepatide runs $250 to $500
US$ 25.70
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