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The fact that these macrophages can restore motility even in the late stages of the disease model indicates that immune cells could be effective drug carriers across the BBB[188] (Fig
The estradiol patch is FDA-approved, bioidentical & plant-based
Through co-encapsulation, such nanoparticles could release BBB modulators in the local tumor site, which adjust the permeability of BBB in the paracellular pathway to ensure more nanoparticles in the same area
197 Cathepsin C Cathepsin C (CTSC) is a widely expressed exocysteine protease that regulates and activates various lysosomal enzymes, including CTSB and CTSD
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