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Two large population-based studies reported that the rate of paracetamol poisoning decreased with age from a peak in adolescence and early adulthood [60, 61]
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6: Initial-rate kinetics of multi-substrate enzyme-catalyzed reactions, 335373 (Elsevier, 2010)
Allison Whitten AstraZeneca reports mixed Phase 3 results across oncology and rare disease AstraZeneca reported mixed late-stage clinical results, with its Claudin 18.2-targeting antibody-drug conjugate sonesitatug vedotin meeting its primary endpoint in patients with previously treated advanced gastric cancer, while rare disease therapy Ultomiris missed the primary endpoint in a Phase 3 trial for thrombotic microangiopathy following haematopoietic stem cell transplantation (HSCT-TMA)
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