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3-month-old female mice (WT or GCLC-KO) were fed with PLX3397 formulated-chow or control chow for 2 months, and brain samples were collected immediately after the end of the feeding period
Based on these findings the authors concluded 'that central GLP-1 is a new physiological mediator of satiety' (Turton, O'Shea, Gunn)
Weight loss plateaus, return of appetite, increased blood sugar readings, and decreased metabolic effects can all signal that your medication has lost potency
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