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Clinical trials of brand-name semaglutide products like Wegovy and Ozempic did not include b12 supplementation as part of the study protocols

"B vitamin status, dietary intake and length of stay in a sample of elderly rehabilitation patients"

Endothelial cells, which make up the inner lining of blood vessels and act as a barrier between the vessel wall and blood, move, proliferate, and differentiate during this process

PMID 16916826

People with digestive conditions such as Crohn's disease, celiac disease, or other inflammatory bowel conditions often have a compromised gut lining and cannot absorb oral B12 efficiently