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Nevertheless, the pooled analysis of 16 trials suggested improvements in the summary measure of patients' global functioning (assessed with the Clinical Global Impressions [CGI-I] scale) after 12 and 24 weeks of (but not after 52 weeks) of ALCAR treatment (1-3 g/day) and in cognitive performance (assessed with the Mini-Mental State Examination [MMSE] scale) after 24 weeks (but not at 12 or 52 weeks) (104)

Mills KL, Goddings AL, Clasen LS, Giedd JN, Blakemore SJ (2014) The developmental mismatch in structural brain maturation during adolescence

For example, earlier this year the FDA approved the use of Wegovy for reducing the risk of heart attacks, strokes, and other cardiovascular events for people who are overweight or obese