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Step 1 Activity modification & self-care Wrist splinting at night neutral-position wrist splints worn at night are one of the most effective non-surgical interventions for early carpal tunnel

Hyperthyroid patients may benefit from L-Carnitine, bugleweed, lemon balm, and short-term iodine

Dry Eyes and Mouth SSA 52kDa & SSA 60kDa : These markers relate to Sjgrens syndrome, which often causes dry eyes and mouth due to reduced tear and saliva production

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Surveillance should comprise routine clinical and specific reproductive-related laboratory monitoring, with defined strategies for treatment cessation if issues emerge