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If cramps are severe, persistent beyond 4-6 weeks of electrolyte correction, or associated with visible muscle swelling, a creatine kinase (CK) level is warranted to rule out rhabdomyolysis, statin-induced myopathy, or other myopathic processes

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Diabetes-related factors, including neuropathy affecting nerves that control the gastrointestinal tract [41, 42] and changes in gut motility [43], can lead to slowed digestion, constipation, and potential bowel obstruction

(84) highlighted the neuroprotective potential of GLP-1 RAs, particularly in reducing protein aggregation and improving mitochondrial function

Experts in nutrition and sports medicine generally recognize the benefits of carnitine, while emphasizing the importance of a balanced approach