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Statins inhibit the activity of the enzyme HMG-CoA reductase, a key enzyme in cholesterol synthesis
Furthermore, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of DEPs mainly included nucleotide excision repair and p53 signaling pathway (Fig
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The metabolite biomarkers discovered through this process could be used as biomarkers for the diagnosis of MDD and remission status, irrespective of exposure to drug treatment, including antidepressants
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