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Abstract AIM: To explore changes in body weight and cardiometabolic risk factors after treatment withdrawal in the STEP 1 trial extension

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Future of transdermal GLP-1 delivery Research on true pharmaceutical-grade transdermal GLP-1 delivery is underway: Microneedle array patches : Use tiny dissolvable needles to deliver medication just below the skin Enhanced transdermal systems : Employ special technologies to improve skin penetration Controlled-release formulations : Designed for sustained delivery over days or weeks Animal studies have shown promising results, with some experimental patches achieving blood levels comparable to those of injections

PMID: 21394604