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Some conditions that can cause this vitamin B12 deficiency include: Atrophic gastritis, an inflammation of the stomach Surgical removal of part of the stomach or intestines Conditions that affect your intestine's ability to absorb nutrients, such as Celiac disease Pancreatic insufficiency Alcoholism Acquired immune deficiency syndrome (AIDS) Some people who don't have enough of a protein called the "intrinsic factor" also have a vitamin B12 deficiency

In addition, 67 participants (81.7%) reported reduced fatigue, 57 (69.5%) felt more energized, 36 (44%) noted clearer focus, and 41 (50%) demonstrated faster recovery and improved performance by the end of the study

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Large population studies have shown that unexplained B12 levels above 813 pg/mL are associated with an increased risk of cancer diagnosis within one year, though the absolute risk for any individual is still relatively low