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[30] [32] Cardiovascular risk reduction is established for specific GLP-1 receptor agonists in type 2 diabetes, and semaglutide 2.4 mg (Wegovy) has an FDA-approved indication for major adverse cardiovascular event risk reduction

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g , Left, volcano plot showing the relative fold change (log 2 ) in whole cell metabolite abundance versus log 10 (P value) from Slc33a1 -knockout KP1 cells expressing a vector control or SLC33A1 cDNA

Due to the controversial pathogenesis of MAFLD, eight classes of new drugs act against different targets (Fig