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In CRISPR-engineered iPSC-derived microglia and neurons, plus primary autopsy microglia and brain tissue, SORL1 deletion triggered endoplasmic reticulum stress, interferon signaling, lipid-droplet accumulation, and impaired phagocytosis
doi: 10.1210/jc.2015-1841 23 RehmanSUsmanZRehmanSAlDraihemMRehmanNRehmanIet al
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