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While peroxidases were known at the time, and their possible involvement in ascorbate oxidation previously noted (Mapson and Goddard 1951), the physiological functions of such enzymes were considered to be as much in H 2 O 2 -dependent oxidations as reductant-dependent H 2 O 2 removal

Only 5% is excreted, the rest is recycled and repackaged as new bile in the liver

If youve experienced it, you know the feeling all too well

Although the efficacy of the same dose is reduced when administered every 48 or 72 h, it is possible that higher doses may elicit effects similar to those of daily treatment

Inhibition of cytochrome P450 enzymes by rhein in rat liver microsomes