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Moreover, GLP-1 receptors are expressed in the cells lining cortical arterioles, and Ex-4 efficiently reversed the constriction of the arterioles induced by OGD or lactate in vitro and increased the CBF in vivo

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stems revealed to exert significant amelioration in APAP-induced apoptosis, inflammation, and oxidative stress through regulation of mitogen-activated protein kinase and caspase-3 signaling pathway (Li et al., 2018)