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It is not removed through the kidneys or liver as much as some other drugs, so it may be safer for people with kidney or liver problems

Berberine, a natural alkaloid and key bioactive constituent of traditional Chinese medicinal herbs, suppresses tubular pyroptosis, thereby mitigating renal inflammation and interstitial fibrosis in DKD (170)

Knee and hip pain improve significantly in users with obesity-related osteoarthritis

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