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Clinical trial data provides objective evidence about efficacy (24.2% weight loss at 48 weeks), safety (88.8% completion rate), side effects (peak at weeks 6-8, resolve by week 12 for most), and discontinuation outcomes (70-80% regain over 12-18 months, not immediately)

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In the United States, nearly half of all adults are now classified as obese, highlighting the urgent need for effective strategies and interventions

Patients with clinically confirmed deficiencies may begin with weekly injections and then transition to a maintenance schedule