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For CME_d, the key residues are E184, D180, R289, and Q359 (Table 4), with E184 forming the most frequent and stable interactions, playing a crucial role
Thus, strategies to boost cell glutathione level are of marked therapeutic significance
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In vitro research models use that clinical literature as a translational reference point, with cell-based GHRH receptor binding assays and pituitary somatotroph cell models providing the upstream mechanistic data