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In pancreatic cancer cells, glutamine supports the production of NADPH via a noncanonical metabolic pathway 29 , and the mitochondrial glutamine transporter is strongly associated with glutaminolysis-induced NADPH generation 16
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doi.org/10.1002/ibd.20453 Seiwerth, S., et al
Ferroptosis in related tissue may appear to be due to exposure to high levels of heme, which may be caused by neovascularization in the prominent nucleus pulposus, and the progressive degeneration of herniated nucleus pulposus is also accelerated (110)
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