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those switched to placebo regained about 14% over the next year. Weight loss slows toward a plateau on a held dose rather than continuing indefinitely

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Some report minor weight changes, but those are often linked to improved appetite from previously undernourished participants rather than targeted fat reduction

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For individuals with a B12 deficiency, injections may help restore energy levels and improve overall well-being, which could indirectly support more active behavior and possibly weight management