History [edit] Descriptions of deficiency effects [edit] Between 1849 and 1887, Thomas Addison described a case of pernicious anemia, William Osler and William Gardner first described a case of neuropathy, Hayem described large red cells in the peripheral blood in this condition, which he called "giant blood corpuscles" (now called macrocytes), Paul Ehrlich identified megaloblasts in the bone marrow, and Ludwig Lichtheim described a case of myelopathy
Those with thiamine and B12 shortages or malabsorption issues are best suited for this treatment
these can include pain, redness, or swelling at the site of the shot, which typically resolve on their own
After amplification, PCR products were electrophoresed on agarose gels and transferred onto nylon membranes using Southern blotting techniques
Hydroxocobalamin, the form of B12 most commonly used in UK clinical practice, may cause a harmless pink or red discolouration of urine