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95% CI 11.0 to 9.42

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The results suggested that TB-500 not only potentially enhanced the viability, angiogenesis, and migratory ability of HUVEC but possibly also promoted the expression of angiopoietin-2 (Ang2), TEK receptor tyrosine kinase 2 (tie2), vascular endothelial growth factor A (VEGFA), NOTCH1 intracellular domain (N1ICD), Notch receptor 3 (Notch3), NF-B, and phosphorylated (p)-p65 in HUVEC

Lastly, we identified a intron variant on chromosome 21,The gene TRPM2 , which is a channel gene is associated with POAG, suggesting that TRPM2 may serve as a potential aqueous humor biomarker for glaucoma 71,72 .(Fig