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The FDA-approved prescribing information states that tesamorelin is not indicated for weight-loss management because it has a weight-neutral effect. In the Phase 3 studies, total body weight changed very little even though the tesamorelin groups demonstrated reductions in: Visceral adipose tissue Waist circumference Trunk fat At the same time, modest increases in lean body mass were reported

Mol Neurobiol 55(4):30073020 Liu Y, Wang L, Pan D, Li M, Li Y, Wang Y, Xu Y, Wang X, Yan J, Wu Q, Lu L, Yuan K, Yang M (2021) PET evaluation of light-induced modulation of microglial activation and GLP-1R expression in depressive rats

Its also important to change where abouts you give the injection every week to avoid injection site reactions and irritation

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Losing even a small amount of weight can have significant advantages, including better blood pressure, blood cholesterol, and blood sugar levels