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doi: 10.1038/s41586-019-1678-1 182 FengJYangHZhangYWeiHZhuZZhuBet al
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What are the most common side effects of oral semaglutide that patients should be aware of
This adaptive response restores glutamate to near normal levels as a compensatory mechanism
Given the high structural conservation between CUL5s binding modes with RBX1 and RBX2 (34), the allosteric regulatory mechanism of neddylation revealed by the CUL5RBX1 model is likely applicable to the CUL5RBX2 complex as well
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