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self-monitor BG daily | | Sulfonylureas (glipizide, glimepiride, glyburide) | Pharmacodynamic: additive insulin release | Hypoglycemia risk | Major | Reduce sulfonylurea 50% at initiation
Leg press: 3 x 10 to 12
Tita AT, Szychowski JM, Boggess K, Dugoff L, Sibai B, Lawrence K, Hughes BL, Bell J, Aagaard K, Edwards RK, et al
Cellular GSSG accumulation, as opposed to GSH reduction, rendered hepatocytes susceptible to TNF cytotoxicity Increased GSSG/GSG ratios in response to H 2 O 2 exposure can stem from both GSH reduction and GSSG accumulation (data not shown)
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