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Preventing Constipation Before It Starts Proactive prevention produces better outcomes than reactive treatment
The PK profiles of intact AMG 133 (GIPR-Ab with at least one attached GLP-1 analogue peptide) and total AMG 133 (GIPR-Ab with or without GLP-1 analogue peptides) follow a biphasic clearance pattern and demonstrate similar initial concentrations between assays with a gradual divergence over the 2-week study period
New England Journal of Medicine 384, 9891002 (2021)
T.SebastianiP.et al (2011)
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