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A total of 2040 differentially expressed genes (DEGs) were identified, with 955 and 1085 genes exhibiting increased expression in mc2r KO and WT, respectively (Supplementary Table 1)
Bone density loss accelerates in the first five to seven years post-menopause, which is the highest-risk window for accelerated osteoporosis and the reason DEXA scans become routine after 50
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