82 In type 2 diabetes-associated cognitive impairment animal models and high-glucose in vitro studies, neuroinflammatory markers, such as IL-1 , TNF-, IL-6, and MCP-1, and inflammatory responses, such as toll-like receptor 4, cyclooxygenase 1 (COX1), COX2, NF-B, leukocyte common antigen, and inducible nitric oxide synthase were increased in the brain
What Is Driving Interest in GLP-1Supporting Supplements
Current clinical studies use a weekly schedule, with dose increases over time to support tolerability
The protein and carbohydrates in the shake may actually enhance creatine uptake
Early data from Alzheimer's trials has generated genuine excitement, proposing that GLP-1 signaling may modulate the neuroinflammation that drives cognitive decline