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[2] This correlation has led to the hypothesis that GHK depletion is not merely a marker of aging but a contributor to it, and that restoring GHK levels could partially reverse age-related tissue decline

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Human and macaque tissue sections were pretreated for 30 min with HIER at 95 C in ER2 (Leica) followed by a 15-min protease treatment and then hybridized with human-specific probes to detect mRNA transcripts for CALCR (483048), PRLH (526568-C2) and GLP1R (519828- C3

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