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Opposite to what was found in male SE offspring, the apoptotic marker caspase-3 level was not changed in females brain suggesting better persevered cell integrity (Chandler et al., There is a significant gender difference in response to maternal SE as shown by us previously (Chan et al., 2000)

However, due to the unpleasant odor of selenols and aliphatic selenides, and also its toxicity the selenium chemistry faced a serious setback

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