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The incision-free procedure is fast and easy, and requires no downtime from normal activities
Beyond its cytoskeletal effects, TB-500 forms functional complexes with PINCH (particularly interesting new cysteine-histidine-rich protein) and integrin-linked kinase (ILK), activating the survival kinase Akt while inhibiting TNF--induced NF-B activation through blocking of RelA/p65 translocation
It remains available for research purposes and personal use, occupying a regulatory gray area similar to other peptides
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L.GaleaE.et al (1993)
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