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Among these, gut microbiota diversity, as a key regulator of metabolism and dietary intake, plays a pivotal role in driving the pathological processes of CVD, particularly hypertension, atherosclerosis, and heart failure ( Hypertension, as a key risk factor for cardio-cerebral vascular diseases, can induce gut microbiota dysbiosis and gut barrier dysfunction

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Upregulation of mGlu2 receptors via NF-B p65 acetylation is involved in the proneurogenic and antidepressant effects of acetyl-L-carnitine