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12 Phase III Liver Detoxification: Elimination Once substances are sent through the liver to be biotransformed in phase I and conjugated in phase II, they must be eliminated

The compound appears well-tolerated in animals at doses well above those producing metabolic effects

Better safe than sorry

However, researchers should always verify that their specific protein is not sensitive to benzyl alcohol, as it may interfere with certain enzymes or delicate protein structures

This dysfunction manifests as reduced vascular response to dilators (particularly to NO and prostacyclin), heightened pro-inflammatory responses leading to vascular wall inflammation, increased oxidative stress contributing to vascular damage, and pathological changes