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These drugs have come about because of demand and lack of access. Multifaceted demand The approval of semaglutide and tirzepatide for type 2 diabetes and later for obesity kickstarted a wave of patient demand, particularly due to the weight reduction effects of both drugs
Increased amounts of thyroxine-binding globulin may result in a reduced clinical response to levothyroxine
However, only a limited number of studies have evaluated clinical outcomes specifically in patients with SID and SIH, as distinct subgroups
Platelet activation, aggregation, and subsequent intra-arterial thrombosis are important steps in atherosclerotic thrombosis, and enhanced platelet reactivity is associated with the degree of terminal organ injury and poor prognosis (73)
Kreider, R
