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Common Skin Symptoms Urticaria (hives) Eczematous rashes Papules or pustules Angioedema Systemic or Severe Symptoms Asthma-like breathing difficulty Anaphylaxis 2 (rare but documented) Worsening of pre-existing dermatologic conditions How APD Differs From PMDD or Other Hormonal Skin Conditions APD involves immune activation, not neurotransmitter sensitivity Symptoms include hives, angioedema, or breathing symptoms (not typical of PMDD) APD resolves rapidly with progesterone withdrawal PMDD causes mood and cognitive symptoms, not immune-mediated skin reactions Histamine can be involved in both PMDD and APD Related: Estrogen and Histamine How Is Autoimmune Progesterone Dermatitis Diagnosed
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Common treatment areas include the abdomen, flanks, thighs, arms, and neck
Ahmad S et al
Low Starting Amount (Research) Amount per measure: 250 mcg 7.5 units (0.075 mL) on a U-100 insulin syringe Schedule: Once weekly in research models (same day each week) Study length: 16+ weeks (raise the amount slowly) Weeks 14 use the starting amount
