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And the promise sounds irresistible: It heals everything. Except it doesnt
We included patients who had been treated with an SGLT2i or GLP-1 RA for at least 6 months and analysed the efficacy, safety and cardio-renal outcomes 5 years after initiation of therapy
Novo is the outlier on breadth - it is betting on all three modalities through four parallel programs
Ferroptosis occurs in osteoblasts (OBs) in an iron-overloaded environment, while bone resorption by OCs is increased, accelerating bone loss, which can be rescued by the antioxidant NAC [93] and the iron chelator DFO [94]
GLP-1s are not yet available in all 50 states
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