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Benzer ekilde, SURMOUNT-1 almasnda tirzepatid 15 mg grubunda bulant oran %31, ishal oran %23.0 ve kusma oran %12.2 olarak raporlanmtr (3)
Tachycardia Most patients see at least some heart rate increase on GLP-1 drugs, but some studies have shown significant jumps into the range of tachycardia
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For instance, a study in 72 obese subjects demonstrated that 20 weeks on semaglutide 2.4mg/weekly caused a 35% decrease in caloric consumption during a free, unrestricted test meal when compared to placebo [13]
This imbalance could lead to potential misestimation of GLP-1 RA effects when generalized to all KTRs with T2DM
