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Significant questions also remain regarding the effect of glycemic control on the development and clinical course of AF
The MHRA advises that metformin commonly reduces B12 levels and recommends testing if deficiency is suspected (for example, in patients with anaemia or neuropathy) and considering periodic monitoring in people with risk factors such as higher doses, longer duration of treatment, or other risk factors for deficiency
2024;261:e230361
Seek immediate medical guidance if adverse symptoms develop
Association between dietary intakes of B vitamins in midlife and cognitive impairment in late-life: the Singapore Chinese Health Study
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