The lack of balance between the production of ROS and the antioxidant defense system of animals will lead to DNA hydroxylation, protein denaturation, lipid peroxidation, cell apoptosis, ultimately lead to cell damage (Yang et al., 2016)
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To reduce flow-induced artefacts, a constant flow of external solution was applied onto cells during baseline recordings and switched to a drug solution during drug application
Limited observational data and case reports suggest that GLP-1 receptor agonists do not adversely affect thyroid function in patients with pre-existing hypothyroidism who are maintained on stable levothyroxine therapy
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