By integrating nanotechnology and biomaterials with rational drug design, researchers are better equipped to harness the therapeutic potential of autophagy modulation in pathological contexts ranging from malignancies to neurodegeneration and chronic inflammatory diseases
Adiponectin reduces glomerular endothelial glycocalyx disruption and restores glomerular barrier function in a mouse model of type 2 diabetes
Kittner SL, Talbott AL, Vishneski SR, Narbaiza J, Shields JS
In laboratory and pre-clinical research settings, native GLP-1 serves as the primary pharmacological reference standard for studying GLP-1 receptor binding, activation, and downstream signalling as well as the broader incretin axis and its connections to pancreatic -cell biology, appetite regulation, gastric motility, cardiovascular function, and neuroprotection
Physiology and ultrastructure of the blood platelet following exposure to hydrogen peroxide