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Similarly, the fetal effects of exenatide, which has a negligible fetal-to-maternal peptide concentration ratio during ex vivo human placental perfusion, are probably due to maternal side effects (34)
The most common side effects for all agents in this drug class are nasopharyngitis, headache, and upper respiratory tract infection
It is noteworthy that a behavioral analysis of Glp1r +/+ , Glp1r +/ and Glp1r/ mouse phenotypes and hippocampal Glp1r gene transfer demonstrated that deficiency of this receptor results in decrements in the acquisition of associative contextual learning which can be improved by hippocampal Glp1r somatic cell gene transfer [45]
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