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95% CI, 2.16-2.80), and high-dose maintenance therapy increased the likelihood by nearly the same proportion (OR, 2.39

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Overall, current evidence supports a model in which gut dysbiosis may promote early intestinal -synuclein pathology, followed by gut-to-brain propagation and chronic neuroinflammation, and ultimately to progressive dopaminergic neurodegeneration

The monthly $149 membership fee is required for all patients after the first month and is billed separately from medication

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