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Second, translational development should focus on dual-functional nanocarriers incorporating A-targeting peptides and RVG29 brain-homing peptides, delivering GPX4 activators or iron chelators with pH/ROS-responsive release to ensure lesion-specific delivery and avoid neurotransmitter synthesis impairment from non-specific iron depletion

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Silver ion binding energies of amino acids: use of theory to assess the validity of experimental silver ion basicities obtained from the kinetic method

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