NAS score, steatosis score, ballooning score and inflammation score of ob/ob-GAN NASH mice were significantly reduction after cinchonine treatment in a dose-dependent manner (Figure 7B-E)
HR effects observed in two independent head-to-head trials of lixisenatide and liraglutide (N = 202
The Patient-Reported Outcome Measurement Information System (PROMIS-10), which measures a combination of physical, mental, and social determinants of health [55], as well as the NeuroQoL-fatigue, an 89 question survey about fatigue [56], correlate with ALSFRS-R scores [57] and are being incorporated more consistently across neurology trials, but are not specific to ALS
Hormonal status (i.e., pregnancy): Maternal toxicity can negatively affect the fetus
Patients struggling with plateaus or regain receive treatment that considers both their physiology and their surgical anatomy