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Table 1, includes studies showing that Empagliflozin improved oxidative stress markers and NYHA functional class in T2DM patients with HFrEF (Nantsupawat et al., 2024)

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Melanotan 1 (MT-1), also known as afamelanotide, is a synthetic tridecapeptide analog of alpha-melanocyte-stimulating hormone (-MSH)

This insulin-stimulating effect could be inhibited by different agents such as diltiazem, yohimbine, propranolol, or a combination of atropine, propranolol, and yohimbine