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Inhibition of ser/gly synthesis using sertraline led to a reduction of galectin-1 expression in PSPH and PSPH V116I overexpressing cells, with a more pronounced and significant effect observed in the PSPH V116I cell model (Fig

The FDA has approved three GLP-1s in particular for both type 2 diabetes treatment and weight loss: Liraglutide (Saxenda, Victoza): While effective, this once-daily injection generally leads to more modest weight loss compared to newer options (its been around since 2014)

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[4] [24] Its principal function is to transport long-chain fatty acids across the mitochondrial membrane, where they undergo beta-oxidation to produce energy

To dissect the upstream regulatory mechanism of miR-29b-3p under Gln deprivation conditions, we integrated transcriptome data (GSE148016) from both Gln+ and Gln- groups, and performed cross-analysis with the predicted upstream transcription factors of miR-29b-3p, ultimately identifying five candidate transcription factors

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