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Severe kidney disease or dehydration risk GI side effects can lead to dehydration and, in vulnerable patients, acute kidney injury
Twice daily means exactly that
10.1038/ncb2220 21 GuarnieriG.SitulinR.BioloG
SciricaBMLincoffAMLingvayIBogdanskiPBuscemiSColhounHet alThe effect of semaglutide on mortality and COVID-19-related deaths: an analysis from the SELECT trial
however, events such as nausea, vomiting, lethargy, sinus tachycardia, respiratory depression, bradycardia, hypotension, hypertension, sedation, somnolence, mydriasis, stupor, hypothermia, drooling, and coma have occurred
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