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Postnatal Growth and Development Behavioral Tests The behavioral tests were performed in a particular room, during the light cycle, at a constant temperature of 22 1 C, with water and food ad libitum

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The aims of this study were to establish a rat model of antenatal opioid dependence and neonatal acute opioid withdrawal (Experiment 1) and to evaluate the effects of NAC on acute opioid withdrawal in the neonatal rat on outcomes of withdrawal behavioral scores and central nervous system (CNS) metabolism (Experiment 2)

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